Resveratrol-Enhanced Human Neural Stem Cell-Derived Exosomes Mitigate MPP+-Induced Neurotoxicity Through Activation of AMPK and Nrf2 Pathways and Inhibition of the NLRP3 Inflammasome in SH-SY5Y Cells

Parkinson’s disease (PD) is a progressive neurodegenerative disorder primarily characterized by the loss of dopaminergic neurons in the substantia nigra. Mitochondrial dysfunction, oxidative stress, and neuroinflammation are recognized as critical pathological mechanisms driving neurodegeneration in...

Full description

Saved in:
Bibliographic Details
Main Authors: Ming-Chang Chiang, Yu-Ping Yang, Christopher J. B. Nicol, Tairui Chiang, Chiahui Yen
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/15/2/294
Tags: Add Tag
No Tags, Be the first to tag this record!