A cell type and state specific gene regulation network inference method for immune regulatory analysis

Abstract The gene regulatory network inference method based on bulk sequencing data not only confuses different types of cells, but also ignores the phenomenon of network dynamic changes with cell state. Single cell transcriptome sequencing technology provides data support for constructing cell type...

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Bibliographic Details
Main Authors: Xiong Li, Kun Rao, Chuang Chen, Yuejin Zhang, Juan Zhou, Xu Meng, Yi Hua, Jie Li, Haowen Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-025-00564-4
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