N4-Hydroxycytidine/molnupiravir inhibits RNA virus-induced encephalitis by producing less fit mutated viruses.

N4-Hydroxycytidine/molnupiravir inhibits RNA virus-induced encephalitis by producing less fit mutated viruses.

A diverse group of RNA viruses have the ability to gain access to the central nervous system (CNS) and cause severe neurological disease. Current treatment for people with this type of infection is generally limited to supportive care. To address the need for reliable antivirals, we utilized a strat...

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Main Authors: Durbadal Ojha, Collin S Hill, Shuntai Zhou, Alyssa Evans, Jacqueline M Leung, Christine A Schneider, Franck Amblard, Tyson A Woods, Raymond F Schinazi, Ralph S Baric, Karin E Peterson, Ronald Swanstrom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012574
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https://doi.org/10.1371/journal.ppat.1012574

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