Combining a 9-month tailored physical exercise program with osimertinib and denosumab in a patient affected by advanced NSCLC with multiple osteolytic bone lesions: A case report

Combining a 9-month tailored physical exercise program with osimertinib and denosumab in a patient affected by advanced NSCLC with multiple osteolytic bone lesions: A case report

A 55-year-old female patient affected by an EGFR mutant NSCLC with multiple lytic bone metastases and two prior pathological fractures, undergoing treatment with osimertinib and denosumab, participated in a 9-month physical exercise program. The exercise program was performed twice a week and consis...

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Bibliographic Details
Main Authors: Anita Borsati, Christian Ciurnelli, Lorenzo Belluomini, Marco Sposito, Jessica Insolda, Linda Toniolo, Ilaria Trestini, Daniela Tregnago, Michele Milella, Federico Schena, Sara Pilotto, Alice Avancini
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Heliyon
Subjects:
Physical activity
Bone metastasis
Lung cancer
Safety
Bone-targeted agents
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025011491
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