The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus

The enzyme activity of sortase A is regulated by phosphorylation in Staphylococcus aureus

In many Gram-positive bacteria, the transpeptidase enzyme sortase A (SrtA) anchors surface proteins to cell wall and plays a critical role in the bacterial pathogenesis. Here, we show that in Staphylococcus aureus, an important human pathogen, the SrtA is phosphorylated by serine/threonine protein k...

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Bibliographic Details
Main Authors: Feifei Chen, Hongxia Di, Yanhui Wang, Chao Peng, Rongrong Chen, Huiwen Pan, Cai-Guang Yang, Haihua Liang, Lefu Lan
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Virulence
Subjects:
Staphylococcus aureus
Sortase A
protein phosphorylation
virulence
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2023.2171641
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https://www.tandfonline.com/doi/10.1080/21505594.2023.2171641

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