Efficacy and safety of Fe-curcumin coordination polymer nanodots to prevent corneal neovascularization in alkali burn models

Efficacy and safety of Fe-curcumin coordination polymer nanodots to prevent corneal neovascularization in alkali burn models

Abstract Alkali burns pose a significant risk of corneal injury, leading to potential blindness. During the progression of alkali burns, heightened oxidation levels can induce corneal damage, resulting in diminished clarity and vision loss. In this study, we chose metallic iron in conjunction with a...

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Main Authors: Yan Huo, Lele Song, Zhihui Han, Yihan Yang, Tianyao Wang, Zhao Chen, Qi Yang, Yongkang Qiu, Wenpeng Huang, Ran Tao, Liang Cheng, Lei Kang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Nanobiotechnology
Subjects:
Fe-curcumin coordination polymer nanodots (Fe-Cur CPNs)
Corneal alkali burn
Neovascularization
Reactive oxygen species
Toxicity
Online Access:https://doi.org/10.1186/s12951-025-03555-z
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https://doi.org/10.1186/s12951-025-03555-z

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