Use of Green Fluorescent Protein/Flp Recombinase Fusion Protein and Flow Cytometric Sorting to Enrich for Cells Undergoing Flp-Mediated Recombination

Flp recombinase has been used extensively for in vivo manipulation of eukaryotic DNA at specific sequences designated as FRT sites. We developed a method to use Flp-mediated recombination without the need for drug resistance or metabolic selection of cells in which recombination has occurred. We gen...

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Bibliographic Details
Main Authors: Daniel E. Sabath, Mi-Hyun Shim
Format: Article
Language:English
Published: Taylor & Francis Group 2000-05-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/00285rr02
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