Fatty acid synthase-derived lipid stores support breast cancer metastasis

Abstract Lipid accumulation is associated with breast cancer metastasis. However, the mechanisms underlying how breast cancer cells increase lipid stores and their functional role in disease progression remain incompletely understood. Herein we quantified changes in lipid metabolism and characterize...

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Main Authors: Chaylen Andolino, Eylem Kulkoyluoglu Cotul, Zilin Xianyu, Yun Li, Divya Bhat, Mitchell Ayers, Kimberly K. Buhman, Stephen D. Hursting, Michael K. Wendt, Dorothy Teegarden
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cancer & Metabolism
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Online Access:https://doi.org/10.1186/s40170-025-00404-3
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