Sepsis Induces a Dysregulated Neutrophil Phenotype That Is Associated with Increased Mortality

Background. Neutrophil dysfunction in sepsis has been implicated in the pathogenesis of multiorgan failure; however, the role of neutrophil extracellular traps (NETs) remains uncertain. We aimed to determine the sequential changes in ex vivo NETosis and its relationship with mortality in patients wi...

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Bibliographic Details
Main Authors: Jaimin M. Patel, Elizabeth Sapey, Dhruv Parekh, Aaron Scott, Davinder Dosanjh, Fang Gao, David R. Thickett
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2018/4065362
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