Inhibitory Effect on the Tyrosinase Activity and Low Cytotoxicity of Monounsaturated Long-Chain Chelating Fatty Ester

Inhibitory Effect on the Tyrosinase Activity and Low Cytotoxicity of Monounsaturated Long-Chain Chelating Fatty Ester

Abstract In the present study, 5-Hydroxy-2-(Oleoyloxymethyl) -4H-pyran-4-one (KMO 3), and their chelated with Cu(II) and Fe(III) ions were synthesized to explore their inhibitory activity against tyrosinase and cytotoxicity. To this end, the structures of the obtained compounds were confirmed by ATR...

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Main Authors: ANTONIO SERGIO C. CARVALHO, TATIANA N. PEDROSA, HERONILDES A. DANTAS FILHO, RAQUEL C. MONTENEGRO, EMERSON S. LIMA, MARNE C. DE VASCONCELLOS, ALBERDAN S. SANTOS
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2025-01-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
kojic acid
oleic acid
conjugates chelating pyrone-fatty Acid
ATR/FT-IR
melanoma
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652024000700504&lng=en&tlng=en
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