Large-scale genomic analysis reveals significant role of insertion sequences in antimicrobial resistance of Acinetobacter baumannii

Large-scale genomic analysis reveals significant role of insertion sequences in antimicrobial resistance of Acinetobacter baumannii

ABSTRACT Acinetobacter baumannii, a prominent nosocomial pathogen renowned for its extensive resistance to antimicrobial agents, poses a significant challenge in the accurate prediction of antimicrobial resistance (AMR) from genomic data. Despite thorough researches on the molecular mechanisms of AM...

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Main Authors: Fei Xie, Lifeng Wang, Song Li, Long Hu, Yanhua Wen, Xuming Li, Kun Ye, Zhimei Duan, Qi Wang, Yuanlin Guan, Ye Zhang, Qiqi Shi, Jiyong Yang, Han Xia, Lixin Xie
Format: Article
Language:English
Published: American Society for Microbiology 2025-03-01
Series:mBio
Subjects:
antimicrobial resistance
random-forest
insertion sequence
IS-ARG pairs
Online Access:https://journals.asm.org/doi/10.1128/mbio.02852-24
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https://journals.asm.org/doi/10.1128/mbio.02852-24

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