Integrative genomic analysis identifies DPP4 inhibition as a modulator of FGF17 and PDGFRA downregulation and PI3K/Akt pathway suppression leading to apoptosis
IntroductionProstate cancer (PCa) remains a significant global health challenge despite advancements in treatment strategies. There is a need to explore the molecular heterogeneity of PCa to facilitate the development of personalized treatment approaches. This study investigates the molecular hetero...
Saved in:
| Main Authors: | Kiran Kumar Chitluri, Emerson Isaac Arnold |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
|
| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1606914/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Expert committee on novel DPP-4 inhibitor TRADJENTA (linagliptin) in treatment of type 2 diabetes mellitus
by: Editorial team Diabetes Mellitus
Published: (2012-06-01) -
Linagliptin synergizes with cPLA2 inhibition to enhance temozolomide efficacy by interrupting DPP4-mediated EGFR stabilization in glioma
by: Dongyuan Su, et al.
Published: (2025-07-01) -
New prospects in the treatment of diabetes mellitus
by: Minara Shamkhalovna Shamkhalova, et al.
Published: (2012-12-01) -
DPP-IV Inhibition by Solubilized Elastin Peptides from Yellowtail Bulbus Arteriosus Suppresses Ultraviolet-B-Induced Photoaging in Hairless Mice
by: Kumiko Takemori, et al.
Published: (2024-12-01) -
Russian Association of Endocrinologists reports commencement of Trajenta clinical use
by: Editorial team Diabetes Mellitus
Published: (2012-12-01)