HuR inhibition overcomes cFLIP-mediated doxorubicin resistance in triple-negative breast cancer

Abstract Triple-negative breast cancer (TNBC) presents therapeutic challenges due to limited targeted treatment options and resistance to chemotherapy drugs, such as doxorubicin. This study investigated doxorubicin resistance mechanisms and a strategy to overcome it. A doxorubicin-resistant cell sub...

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Bibliographic Details
Main Authors: Lanjing Wei, Sung Hae Kim, Ahlam M. Armaly, Jeffrey Aubé, Liang Xu, Xiaoqing Wu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00780-x
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