Region-specific brain decellularized extracellular matrix promotes cell recovery in an in vitro model of stroke

Region-specific brain decellularized extracellular matrix promotes cell recovery in an in vitro model of stroke

Abstract Brain decellularized extracellular matrix (ECM) can be an attractive scaffold capable of mimicking the native ecosystem of the central nervous system tissue. We studied the in vitro response of neural cultures exposed to region-specific brain decellularized ECM scaffolds from three distinct...

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Main Authors: Diego Reginensi, Didio Alberto Ortiz, Bernardino Denis, Solangel Castillo, Andrea Burillo, Nathalie Khoury, Jing Xu, Maria Lucia Dam, Anthony A. Hurtado Escobar, Kunjan R. Dave, Miguel A. Perez-Pinzon, Rolando A. Gittens
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Tissue engineering
Decellularized scaffold
Brain extracellular matrix
Oxygen-glucose deprivation (OGD).
Online Access:https://doi.org/10.1038/s41598-025-95656-w
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https://doi.org/10.1038/s41598-025-95656-w

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