The HIF-1α/miR-145b/Angpt2 axis attenuates renal fibrosis induced by unilateral renal ischemia–reperfusion

Abstract Background Renal fibrosis is a major pathological feature in chronic kidney disease, and is considered the final common pathway for virtually all progressive kidney diseases. Although a large amount of progress has been made in understanding renal fibrosis, the pathogenesis is very complex...

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Bibliographic Details
Main Authors: Bingyou Cheng, Shang Huang, Lin Zhou, Pei Zhu, Zhongpu Li, Liang Hu, Jingsong Liu, Kejian Zhu
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Renal Replacement Therapy
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Online Access:https://doi.org/10.1186/s41100-025-00608-9
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