Generation and clearance of myelin debris after spinal cord injury

Generation and clearance of myelin debris after spinal cord injury

Traumatic spinal cord injury often leads to the disintegration of nerve cells and axons, resulting in a substantial accumulation of myelin debris that can persist for years. The abnormal buildup of myelin debris at sites of injury greatly impedes nerve regeneration, making the clearance of debris wi...

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Bibliographic Details
Main Authors: Chaoyuan Li, Wenqi Luo, Irshad Hussain, Renrui Niu, Xiaodong He, Chunyu Xiang, Fengshuo Guo, Wanguo Liu, Rui Gu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-04-01
Series:Neural Regeneration Research
Subjects:
foam cells
lipid droplets
lipid metabolism
macrophages
microglia
myelin debris
myelin proteins
myelin sheath
nerve regeneration
phagocytosis
spinal cord injury
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-01405
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