Establishment of an Intestinal Fibrosis Model Associated with Inflammatory Bowel Disease in VDR-/- Mice Induced by Helicobacter hepaticus Infection and Mechanism Exploration

ObjectiveTo employ Helicobacter hepaticus (H.hepaticus, H.h) to induce intestinal fibrosis in vitamin D receptor deletion (VDR-/-) mice, thereby establishing a model of inflammatory bowel disease to investigate its pathological characteristics and underlying mechanisms.MethodsFive male WT and five m...

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Bibliographic Details
Main Authors: WU Zhihao, CAO Shuyang, ZHOU Zhengyu
Format: Article
Language:zho
Published: Editorial Office of Laboratory Animal and Comparative Medicine 2025-02-01
Series:Shiyan dongwu yu bijiao yixue
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Online Access:https://www.slarc.org.cn/dwyx/article/2025/1674-5817/1674-5817-2025-45-1-37.shtml
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