Optimization of the Production of Vaccine Epitopes from <i>Clostridium novyi</i> Alpha-Toxin Using Strains of Recombinant <i>Escherichia coli</i>

Optimization of the Production of Vaccine Epitopes from <i>Clostridium novyi</i> Alpha-Toxin Using Strains of Recombinant <i>Escherichia coli</i>

<i>Clostridium novyi</i> is a common pathogen in domestic animals and humans, and alpha-toxin is the main cause of its pathogenesis. Because it is a fastidious organism, obtaining alpha-toxin is expensive. Therefore, we proposed an in silico study to synthesize epitopes in cultures of Es...

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Main Authors: Mellanie K. C. Félix, Tullio T. Deusdará, Hélio S. Brito, Gil R. Santos, Eduardo R. T. Leite, Vanessa M. Chapla, Kelvinson F. Viana, Igor V. Brandi, Maria Edilene M. de Almeida, Luis André M. Mariúba, Paulo A. Nogueira, Elizângela F. da Silva, Juliane C. Glória, Raquel Stefanni R. da Silva, Darleide dos S. Braga, Anderson M. de Lima, Andreimar M. Soares, Alex Sander R. Cangussu
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Microorganisms
Subjects:
alpha-toxin
vaccine epitopes
<i>C. novyi</i>
clostridiosis
bioprocesses
DE3
Online Access:https://www.mdpi.com/2076-2607/13/7/1481
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