Combination Adjuvants Enhance Recombinant H5 Hemagglutinin Vaccine Protection Against High-Dose Viral Challenge in Chickens

Combination Adjuvants Enhance Recombinant H5 Hemagglutinin Vaccine Protection Against High-Dose Viral Challenge in Chickens

Background: Recombinant avian influenza subunit vaccines often require adjuvants to enhance immune responses. This study aims to evaluate the immune-enhancing potential of seven combination adjuvants in specific pathogen-free (SPF) chickens. Methods: SPF chickens were vaccinated with combinations of...

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Bibliographic Details
Main Authors: Yanjuan He, Jiaxin Wang, Lanyan Chi, Yajing Dong, Huixin Chen, Xiaocui Meng, Ming Liao, Yongwen Luo, Huiying Fan
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Vaccines
Subjects:
avian influenza
H5 subtype
adjuvanted vaccine
Quil-A
TLR agonist
Online Access:https://www.mdpi.com/2076-393X/12/12/1448
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https://www.mdpi.com/2076-393X/12/12/1448

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