Polygenic and pharmacogenomic contributions to medication dosing: a real-world longitudinal biobank study
Abstract Background Understanding interindividual variability in medication dosing is central to precision medicine. Despite significant pharmacogenomic (PGx) insights into key biological pathways influencing drug response, the polygenic contribution to dose variability and the potential of electron...
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| Main Authors: | Silva Kasela, Laura Birgit Luitva, Kristi Krebs, Estonian Biobank Research Team, Märt Möls, Lili Milani, Maris Alver |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-025-06782-y |
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