USP39 regulates pyruvate handling in non-small cell lung cancer

Abstract The ubiquitin-specific peptidase 39 (USP39) belongs to the USP family of cysteine proteases representing the largest group of human deubiquitinases (DUBs). While the oncogenic function of USP39 has been investigated in various cancer types, its roles in non-small cell lung cancer (NSCLC) re...

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Bibliographic Details
Main Authors: Tina Becirovic, Boxi Zhang, Helin Vakifahmetoglu-Norberg, Vitaliy O. Kaminskyy, Elena Kochetkova, Erik Norberg
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02264-0
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