Effect of VPAC1 Blockade on Adipose Tissue Formation and Composition in Mouse Models of Nutritionally Induced Obesity
Background. The pituitary adenylate cyclase activating polypeptide (PACAP) may affect adipogenesis and adipose tissue formation through interaction with its G-protein-coupled receptor VPAC1. Methods. We have used a monoclonal antibody (MAb 23A11) blocking VPAC1 in mouse models of nutritionally induc...
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Main Authors: | H. Roger Lijnen, Kathleen Freson, Marc F. Hoylaerts |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | Journal of Obesity |
Online Access: | http://dx.doi.org/10.1155/2010/359527 |
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