Effect of VPAC1 Blockade on Adipose Tissue Formation and Composition in Mouse Models of Nutritionally Induced Obesity

Background. The pituitary adenylate cyclase activating polypeptide (PACAP) may affect adipogenesis and adipose tissue formation through interaction with its G-protein-coupled receptor VPAC1. Methods. We have used a monoclonal antibody (MAb 23A11) blocking VPAC1 in mouse models of nutritionally induc...

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Bibliographic Details
Main Authors: H. Roger Lijnen, Kathleen Freson, Marc F. Hoylaerts
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Obesity
Online Access:http://dx.doi.org/10.1155/2010/359527
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