Genetic effects of circulating hormone and proteome on amyotrophic lateral sclerosis identified by Mendelian randomization
Abstract Altered circulating hormones in ALS patients have been widely reported by previous observational studies, but whether these relationships are causal is unclear. Moreover, the potential therapeutic targets for ALS and the effects of plasma protein fluctuation on ALS progression are not fully...
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| Main Authors: | Xinyue Fan, Yinting Zeng, Feifei Zhang, Yang Xu, Qixuan Duan, Shuting Long, Yumeng Lin, Kai Wang, Li Jiang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-95151-2 |
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