Ion channel classification through machine learning and protein language model embeddings

Ion channel classification through machine learning and protein language model embeddings

Ion channels are critical membrane proteins that regulate ion flux across cellular membranes, influencing numerous biological functions. The resource-intensive nature of traditional wet lab experiments for ion channel identification has led to an increasing emphasis on computational techniques. This...

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Bibliographic Details
Main Authors: Ghazikhani Hamed, Butler Gregory
Format: Article
Language:English
Published: De Gruyter 2024-11-01
Series:Journal of Integrative Bioinformatics
Subjects:
ion channels
membrane proteins
transmembrane proteins
drug discovery
protein language models
convolutional neural network
Online Access:https://doi.org/10.1515/jib-2023-0047
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https://doi.org/10.1515/jib-2023-0047

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