Preserving the Surface Activity of Lung Surfactant Using Soft Nebulization

Inhalable aerosols produced by nebulization offer a promising noninvasive route for lung drug delivery. Yet, high shear stresses during nebulization are highly detrimental to many complex biopharmaceuticals, such as lung surfactants, leading to degradation and further reducing their efficacy. Herein...

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Bibliographic Details
Main Authors: Kaili Xie, Thijs Varkevisser, Antoine Deblais, Wes Onland, Anton H. van Kaam, Daniel Bonn, Cees J. M. van Rijn
Format: Article
Language:English
Published: Wiley-VCH 2025-07-01
Series:Small Science
Subjects:
Online Access:https://doi.org/10.1002/smsc.202400639
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