Misregulation of the Ubiquitin–Proteasome System and Autophagy in Muscular Dystrophies Associated with the Dystrophin–Glycoprotein Complex

Misregulation of the Ubiquitin–Proteasome System and Autophagy in Muscular Dystrophies Associated with the Dystrophin–Glycoprotein Complex

The stability of the sarcolemma is severely impaired in a series of genetic neuromuscular diseases defined as muscular dystrophies. These are characterized by the centralization of skeletal muscle syncytial nuclei, the replacement of muscle fibers with fibrotic tissue, the release of inflammatory cy...

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Bibliographic Details
Main Authors: Manuela Bozzi, Francesca Sciandra, Maria Giulia Bigotti, Andrea Brancaccio
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
dystrophin
dystroglycan
dystroglycanopathies
proteasome degradation
autophagy
Online Access:https://www.mdpi.com/2073-4409/14/10/721
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https://www.mdpi.com/2073-4409/14/10/721

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