A first-in-human, prospective pilot trial of umbilical cord-derived mesenchymal stem cell eye drops therapy for patients with refractory non-Sjögren's and Sjögren's syndrome dry eye disease

A first-in-human, prospective pilot trial of umbilical cord-derived mesenchymal stem cell eye drops therapy for patients with refractory non-Sjögren's and Sjögren's syndrome dry eye disease

Abstract Background Patients with refractory dry eye disease (DED) often face the threat of diminished visual quality and have limited responses to existing treatments. Ocular injection of Mesenchymal stem cells (MSCs) has recently emerged as a promising new therapeutic strategy for DED. Topical eye...

Full description

Saved in:
Bibliographic Details
Main Authors: Di Zhang, Taige Chen, Qi Liang, Xuebing Feng, Jiaxuan Jiang, Zeying Chen, Yun Tang, Yiran Chu, Bin Wang, Kai Hu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cell eye drops
Non-Sjögren’s dry eye
Sjögren's syndrome dry eye
Clinical efficacy
Safety
Tear proteomic analysis
Online Access:https://doi.org/10.1186/s13287-025-04292-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items