Simple Strategy for Sequencing cDNA Clones

We describe a simple method for constructing subclones containing overlapping nested deletions from cDNA clones (both λ phage clones and plasmid clones). A PCRamplified insert is partially digested with 4-cutter restriction enzyme(s). Complete digestion of this DNA with two restriction enzymes, havi...

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Bibliographic Details
Main Authors: Ling-Wen Zeng, Martin Kreitman
Format: Article
Language:English
Published: Taylor & Francis Group 1996-09-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/96213st01
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