Targeting epigenetic regulators to overcome drug resistance in the emerging human fungal pathogen Candida auris

Targeting epigenetic regulators to overcome drug resistance in the emerging human fungal pathogen Candida auris

Abstract The rise of drug-resistant fungal species, such as Candida auris, poses a serious threat to global health, with mortality rates exceeding 40% and resistance rates surpassing 90%. The limited arsenal of effective antifungal agents underscores the urgent need for novel strategies. Here, we sy...

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Main Authors: Yuping Zhang, Lingbing Zeng, Xinhua Huang, Yuanyuan Wang, Guangsheng Chen, Munika Moses, Yun Zou, Sichu Xiong, Wenwen Xue, Yanmei Dong, Yueru Tian, Ming Guan, Lingfei Hu, Zhe Yin, Dongsheng Zhou, Xiaotian Huang, Changbin Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59898-6
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https://doi.org/10.1038/s41467-025-59898-6

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