Ferroptosis in periodontitis: mechanisms, impacts, and systemic connections

Abstract Periodontitis is a chronic inflammatory disease initiated by plaque microorganisms, with the regulatory mechanisms of its progression being a primary research focus. Ferroptosis, a unique form of cell death driven by iron-dependent lipid peroxidation, has been increasingly recognized for it...

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Bibliographic Details
Main Authors: Peng Guan, Qijun Ruan, Jiatong Li, Mengying Xi, Weijuan Qi, Kang I. Ko, Jia Ni
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02550-5
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