Transitional and CD21− PD-1+ B cells are associated with remission in early rheumatoid arthritis

Transitional and CD21− PD-1+ B cells are associated with remission in early rheumatoid arthritis

Abstract Background Early initiation of effective treatment is associated with positive long-term prognosis for patients with rheumatoid arthritis (RA). Currently, there are no biomarkers in clinical use to predict treatment response. A predictor of treatment response may be the B-cell compartment,...

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Main Authors: Sarah McGrath, Boel Sundbeck, Katrin Thorarinsdottir, Charlotte A. Jonsson, Alessandro Camponeschi, Monica Leu Agelii, Anna-Karin H. Ekwall, Merete Lund Hetland, Mikkel Østergaard, Till Uhlig, Michael Nurmohamed, Jon Lampa, Dan Nordström, Kim Hørslev-Petersen, Bjorn Gudbjornsson, Gerdur Gröndal, Ronald van Vollenhoven, Anna Rudin, Inga-Lill Mårtensson, Inger Gjertsson
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Rheumatology
Subjects:
Early rheumatoid arthritis
B cell
Transitional B cell
PD-1
Rheumatoid arthritis
Remission
Online Access:https://doi.org/10.1186/s41927-025-00487-x
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https://doi.org/10.1186/s41927-025-00487-x

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