V-ATPase in cancer: mechanistic insights and therapeutic potentials

Abstract Vacuolar-type H+-ATPase (V-ATPase) is a crucial proton pump that plays an essential role in maintaining intracellular pH homeostasis and a variety of physiological processes. This review provides an in-depth exploration of the structural components, functional mechanisms, and regulatory mod...

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Bibliographic Details
Main Authors: Tingting Chen, Xiaotan Lin, Shuo Lu, Bo Li
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-024-01998-9
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