Structure Elucidation, Biosynthetic Gene Cluster Distribution, and Biological Activities of Ketomemicin Analogs in <i>Salinispora</i>

Structure Elucidation, Biosynthetic Gene Cluster Distribution, and Biological Activities of Ketomemicin Analogs in <i>Salinispora</i>

Pseudopeptides are attractive agents for protease inhibition due to their structural similarities to the natural substrates of these enzymes, as well as their enhanced stability and resistance to enzymatic degradation. We report three new ketomemicin pseudopeptides (<b>1</b>–<b>3&l...

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Bibliographic Details
Main Authors: Gabriel Castro-Falcón, Dulce G. Guillén-Matus, Elany Barbosa Da Silva, Wentao Guo, Alicia Ross, Mateus Sá Magalhães Serafim, Thaís Helena Maciel Fernandes, Dean J. Tantillo, Anthony J. O’Donoghue, Paul R. Jensen
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Marine Drugs
Subjects:
natural products
<i>Salinispora</i>
ketomemicins
pseudopeptides
Online Access:https://www.mdpi.com/1660-3397/23/3/126
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