Oversized nanodiscs for combined structural and functional investigation of multicomponent membrane protein systems

Abstract Membrane proteins are fundamental to many crucial cellular processes but removing them from their native environment for structural and functional studies creates experimental challenges. Numerous strategies have been developed to replicate native-like membrane environments in vitro for mem...

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Bibliographic Details
Main Authors: Bozhidar S. Ivanov, Judy Hirst
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-15035-3
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