GSDMD-NETs in patients with sepsis-induced coagulopathy and their interaction with glycocalyx damage

IntroductionNeutrophil extracellular traps (NETs) play a critical role in inflammation and coagulation imbalance. Recent studies have demonstrated that activation of gasdermin D (GSDMD) protein and its pore-forming activity are essential drivers of NET generation. This study investigated the associa...

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Bibliographic Details
Main Authors: Xiaoxi Shan, Songmei Yu, Zhaoying Tang, Ping Yang, Lixia Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1624128/full
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