Construction of TRIF-knockout NA and BHK-21 cell lines and effect on rabies virus proliferation efficiency
ObjectiveTo construct TIR-domain-containing adaptor-inducing interferon β (TRIF) gene knockout mouse NA cell line and hamster BHK-21 cell line using CRISPR/Cas9 technology, evaluate the proliferative capacity of rabies virus (RABV) in these knockout cell lines, and investigate TRIF function during R...
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| Main Authors: | Weitao HUANG, Jiaqi LI, Yao PENG, Xiangping YIN, Xiaofeng GUO, Jun LUO |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
South China Agricultural University
2025-09-01
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| Series: | Huanan Nongye Daxue xuebao |
| Subjects: | |
| Online Access: | https://journal.scau.edu.cn/article/doi/10.7671/j.issn.1001-411X.202502016 |
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