System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock.
The mammalian circadian timing system consists of a master pacemaker in neurons of the suprachiasmatic nucleus (SCN) and clocks of a similar molecular makeup in most peripheral body cells. Peripheral oscillators are self-sustained and cell autonomous, but they have to be synchronized by the SCN to e...
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| Main Authors: | Benoît Kornmann, Olivier Schaad, Hermann Bujard, Joseph S Takahashi, Ueli Schibler |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-02-01
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| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0050034&type=printable |
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