System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock.

The mammalian circadian timing system consists of a master pacemaker in neurons of the suprachiasmatic nucleus (SCN) and clocks of a similar molecular makeup in most peripheral body cells. Peripheral oscillators are self-sustained and cell autonomous, but they have to be synchronized by the SCN to e...

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Bibliographic Details
Main Authors: Benoît Kornmann, Olivier Schaad, Hermann Bujard, Joseph S Takahashi, Ueli Schibler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.0050034&type=printable
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