Osteosarcoma Cells and Undifferentiated Human Mesenchymal Stromal Cells Are More Susceptible to Ferroptosis than Differentiated Human Mesenchymal Stromal Cells

Osteosarcoma Cells and Undifferentiated Human Mesenchymal Stromal Cells Are More Susceptible to Ferroptosis than Differentiated Human Mesenchymal Stromal Cells

Current research suggests that promoting ferroptosis, a non-apoptotic form of cell death, may be an effective therapy for osteosarcoma, while its inhibition could facilitate bone regeneration and prevent osteoporosis. Our objective was to investigate whether the susceptibility to and regulation of f...

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Bibliographic Details
Main Authors: Yuliya D. Smirnova, Dominik Hanetseder, Lukas Derigo, Andreas Sebastian Gasser, Annette Vaglio-Garro, Simon Sperger, Regina Brunauer, Olga S. Korneeva, Johanna Catharina Duvigneau, Darja Marolt Presen, Andrey V. Kozlov
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Antioxidants
Subjects:
ferroptosis
osteosarcoma
Erastin
RSL3
Ferrostatin-1
Online Access:https://www.mdpi.com/2076-3921/14/2/189
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