Identification of anisomycin, prodigiosin and obatoclax as compounds with broad-spectrum anti-parasitic activity.

Identification of anisomycin, prodigiosin and obatoclax as compounds with broad-spectrum anti-parasitic activity.

Parasitic infections are a major source of human suffering, mortality, and economic loss, but drug development for these diseases has been stymied by the significant expense involved in bringing a drug though clinical trials and to market. Identification of single compounds active against multiple p...

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Main Authors: Gretchen Ehrenkaufer, Pengyang Li, Erin E Stebbins, Monica M Kangussu-Marcolino, Anjan Debnath, Corin V White, Matthew S Moser, Joseph DeRisi, Jolyn Gisselberg, Ellen Yeh, Steven C Wang, Ana Hervella Company, Ludovica Monti, Conor R Caffrey, Christopher D Huston, Bo Wang, Upinder Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008150
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https://doi.org/10.1371/journal.pntd.0008150

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