Crosstalk between H2A variant-specific modifications impacts vital cell functions.

Selection of C-terminal motifs participated in evolution of distinct histone H2A variants. Hybrid types of variants combining motifs from distinct H2A classes are extremely rare. This suggests that the proximity between the motif cases interferes with their function. We studied this question in flow...

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Bibliographic Details
Main Authors: Anna Schmücker, Bingkun Lei, Zdravko J Lorković, Matías Capella, Sigurd Braun, Pierre Bourguet, Olivier Mathieu, Karl Mechtler, Frédéric Berger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009601
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