Effects of bortezomib on intracellular antioxidant and apoptosis in HepG2cells

Bortezomib, as a proteasome inhibitor, is used in clinical trials related to solid cancers. However, its use is not always associated with a good response to treatment. Taking into account the above, we decided to analyze the effect of the time-dependency (24 vs. 48 h) and the dose-dependency of bor...

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Main Authors: Grażyna Świderska-Kołacz, Magdalena Madej, Szymon Zmorzynski, Wojciech Styk, Iwona Surowiec, Bożena Witek, Anna Wojciechowska, Joanna Czerwik-Marcinkowska, Anna Nowakowska
Format: Article
Language:English
Published: PeerJ Inc. 2025-04-01
Series:PeerJ
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Online Access:https://peerj.com/articles/19235.pdf
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