Localized network damage related to white matter hyperintensities is linked to worse outcome after severe stroke

Localized network damage related to white matter hyperintensities is linked to worse outcome after severe stroke

Abstract White matter hyperintensities of presumed vascular origin (WMH) are associated with various clinical sequelae. In stroke patients, the total WMH burden is linked to recurrent cerebrovascular events and worse clinical outcomes. As WMH also affect the integrity of large-scale structural brain...

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Main Authors: Samuel C. Olszówka, Benedikt M. Frey, Jan F. Feldheim, Lukas Frontzkowski, Paweł P. Wróbel, Winifried Backhaus, Focko L. Higgen, Hanna Braaß, Silke Wolf, Chi-un Choe, Marlene Bönstrup, Bastian Cheng, Götz Thomalla, Philipp J. Koch, Fanny Quandt, Christian Gerloff, Robert Schulz
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Neurological Research and Practice
Subjects:
Cerebral small vessel disease
WMH
Brain reserve
Functional outcome
Rehabilitation
Online Access:https://doi.org/10.1186/s42466-025-00416-w
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https://doi.org/10.1186/s42466-025-00416-w

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