Phenotypic Screening of H<sub>1</sub>-Antihistamines Identifies Promethazine and Rupatadine as Active Compounds Against <i>Toxocara canis</i> Infective Larvae

Phenotypic Screening of H<sub>1</sub>-Antihistamines Identifies Promethazine and Rupatadine as Active Compounds Against <i>Toxocara canis</i> Infective Larvae

<b>Background</b>: Parasitic worm infections remain among the most prevalent and neglected health issues worldwide, affecting both humans and animals. Toxocariasis, caused by <i>Toxocara</i> spp., is a widespread zoonosis with significant public health and economic implicatio...

Full description

Saved in:
Bibliographic Details
Main Authors: Taís C. Silva, Julia Godoy-Silva, Monique C. Amaro, João V. Silva-Silva, Thiago H. Doring, Leonardo L. G. Ferreira, Adriano D. Andricopulo, Josué de Moraes
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pharmaceuticals
Subjects:
<i>Toxocara canis</i>
H1 antihistamine
β-tubulin
density functional theory
molecular docking
Online Access:https://www.mdpi.com/1424-8247/18/7/997
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1424-8247/18/7/997

Similar Items