513 A CTS team approach to investigate skeletal muscle diseases and countermeasures in a donor-derived bioengineered muscle platform

Objectives/Goals: Our team has developed a 24-well donor-derived skeletal muscle microphysiological system (MPS) to study signaling pathways associated with a variety of muscle diseases. 3D muscle will be utilized to evaluate pharmacologic interventions for these muscle conditions to improve both mu...

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Bibliographic Details
Main Authors: Karly Caples, Vinicius Mariani, Elisabeth Barton, Siobhan Malany
Format: Article
Language:English
Published: Cambridge University Press 2025-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S205986612401094X/type/journal_article
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