Prediction of Parallel Artificial Membrane Permeability Assay of Some Drugs from their Theoretically Calculated Molecular Descriptors

Parallel artificial membrane permeation assays (PAMPA) have been extensively utilized to determine the drug permeation potentials. In the present work, the permeation of miscellaneous drugs measured as flux by PAMPA (logF) of 94 drugs, are predicted by quantitative structure property relationships m...

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Bibliographic Details
Main Authors: E. Konoz, Amir H. M. Sarrafi, S. Ardalani
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2011/637368
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