Sporadic detection of vaccine-derived poliovirus type 2 using next-generation sequencing in Canadian wastewater in August of 2022

Sporadic detection of vaccine-derived poliovirus type 2 using next-generation sequencing in Canadian wastewater in August of 2022

Abstract In July 2022, an unvaccinated young adult living in Rockland County, New York became paralyzed due to a vaccine-derived poliovirus type 2 (VDPV2) infection that was internationally transmitted. Wastewater surveillance in New York State uncovered VDPV2 in neighboring counties, showing silent...

Full description

Saved in:

Bibliographic Details
Main Authors:	Grace E. Seo, Russell Mandes, Nathan D. Wright, Justin P. Hawkins, Anneliese Landgraff, Ravinder Lidder, Umar Mohammed, Chand S. Mangat, Anne-Sophie Michel, Judith Fafard, Darian Hole, Andrea D. Tyler, Marli Vlok, Elsie Grudeski, Tim F. Booth, Anna Majer
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-04-01
Series:	Scientific Reports
Subjects:	Poliovirus Vaccine-derived poliovirus type 2 (VDPV2) Wastewater surveillance Next generation sequencing Nanopore Direct detection
Online Access:	https://doi.org/10.1038/s41598-025-92912-x
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Community surveillance after detection of poliovirus in the environment in London, United Kingdom, October 2022 to April 2023
by: Maria Zambon
Published: (2025-04-01)

Supplementary Surveillance of Poliovirus Circulation in the Russian Federation: Results of a Study on Migrant Children of “Risk Group”
by: Olga E. Ivanova, et al.
Published: (2025-05-01)

Genetic characterization of type 3 vaccine-derived poliovirus from a patient with hand, foot, and mouth disease in China
by: Wei Zhang, et al.
Published: (2025-06-01)

Inhibitory Effects of Chalcone on the Replication of Poliovirus in Vitro
by: Baghdad Science Journal
Published: (2013-06-01)

Immunodeficiency-Related Vaccine-Derived Poliovirus (iVDPV) Infections: A Review of Epidemiology and Progress in Detection and Management
by: Concepcion F. Estivariz, et al.
Published: (2024-12-01)

Silent spread of poliovirus type 2 variant (cVDPV) in Gaza
by: Mohd Sayeed Shaikh, et al.
Published: (2025-05-01)

Poliovirus and other enteroviruses in children infected with intestinal parasites in Nigeria
by: Daniel R Adekolujo, et al.
Published: (2015-10-01)

Excretion and clearance of Sabin-like type 3 poliovirus in a child diagnosed with severe combined immunodeficiency
by: Ning Yao, et al.
Published: (2025-12-01)

Occurrence of poliovirus and non-polio enterovirus among children with acute flaccid paralysis in Cameroon from 2015 to 2020
by: Daniel K Njile, et al.
Published: (2024-02-01)

Battle against poliovirus in Pakistan
by: Kaneez Fatima, et al.
Published: (2013-11-01)

Excretion of vaccine polioviruses by the children From closed institutions
by: M. A. Bichurina, et al.
Published: (2014-09-01)

Investigation and response to a type 3 vaccine-derived poliovirus detected in an infant with hand, foot, and mouth disease — Guangdong, China, 2023
by: Jialing Li, et al.
Published: (2025-05-01)

Antisera-Neutralizing Capacity of a Highly Evolved Type 2 Vaccine-Derived Poliovirus from an Immunodeficient Patient
by: Yanan Wu, et al.
Published: (2024-11-01)

Poliomyelitis in modern conditions: achievements and prospects
by: O. E. Ivanova
Published: (2018-07-01)

Immunogenicity of Two Fractional Inactivated Poliovirus Vaccine Doses vs Single Intramuscular Inactivated Poliovirus Vaccine Dose in Infants of Low- and Middle-income Countries: A Prospective Case-control Study
by: Kunal Kumar, et al.
Published: (2024-03-01)

Antiviral Activity of Hen Egg-White Lysozyme on Polio Virus.
by: Oderinde B.S., *, Agbede O. O., Iheukwumere I.N., Ghamba P.E., Medugu J.T., Oku E.I., et al.
Published: (2017-09-01)

Polio Today: State of the Global Eradication Program and Modern Strategy of WHO on Immunization
by: O. E. Ivanova
Published: (2015-04-01)

Absence of poliovirus in apparently healthy school children in Bauchi state, Nigeria
by: Idris Abdullahi Nasir, et al.
Published: (2016-08-01)

Advances and challenges in poliomyelitis vaccines: a comprehensive review of development, production, and global deployment
by: Jia Liang, et al.
Published: (2025-07-01)

Long-Term Persistence of Anti-Poliovirus Antibody Titers After Two-Dose Booster Immunization with Conventional Inactivated Poliovirus Vaccine Among Japanese Adults: 10-Year Observational Study
by: Shinji Fukushima, et al.
Published: (2025-04-01)

Polio Vaccines: Present and Future
by: K. Chumakov, et al.
Published: (2018-06-01)

Frequency of isolation of polioviruses and non polio enteroviruses from patients with acute flaccid paralysis, enterovirus infection and children from groups at risk
by: N. I. Romanenkova, et al.
Published: (2014-09-01)

A potential surrogate for poliovirus in testing the efficacy of hand antiseptics according to the Global Poliovirus Containment Action Plan
by: Eggers, Maren, et al.
Published: (2025-07-01)

Experimental Approaches to the Development of Inactivated Poliovirus Vaccine Based on Sabin Strains
by: A. P. Ivanov, et al.
Published: (2016-08-01)

Monitoring the Risk of Type-2 Circulating Vaccine-Derived Poliovirus Emergence During Roll-Out of Type-2 Novel Oral Polio Vaccine
by: Corey M. Peak, et al.
Published: (2024-11-01)

Importance of virological surveillance after migrants from polio high-risk territories for poliomyelitis monitoring in the Russian Federation
by: Olga I. Kanaeva, et al.
Published: (2024-12-01)

Acute flaccid paralysis indicators during the COVID-19 pandemic in Mozambique 2019 - 2020
by: Beatriz Nhantumbo, et al.
Published: (2024-08-01)

Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication Efforts
by: Vachagan Harutyunyan, et al.
Published: (2024-12-01)

Antiviral Development for the Polio Endgame: Current Progress and Future Directions
by: Hang Xie, et al.
Published: (2024-11-01)

Promising opportunities to improve polio vaccines
by: E. E. Evreinova, et al.
Published: (2022-07-01)

Vaccination coverage and factors associated with incomplete polio vaccine schedule in children born in 2017-2018, in state capitals and interior region municipalities of Northeast Brazil
by: Alberto Novaes Ramos Jr., et al.
Published: (2024-12-01)

Harnessing laboratory data for poliovirus eradication: contributions of the Africa regional polio laboratory data management team, 2022 – 2024
by: Brook Tesfaye, et al.
Published: (2025-01-01)

Application of Ion Exchange Chromatography in the Development of Technology to Obtain Inactivated Poliovirus Vaccine
by: A. N. Piniaeva, et al.
Published: (2022-11-01)

Circulating vaccine-derived poliovirus outbreak in Chiengi District, Zambia, September 2019
by: Chipoya Musole, et al.
Published: (2024-09-01)

MODERN POSSIBILITIES OF VIROLOGICAL DIAGNOSTICS OF POLIOMYELITIS
by: E. A. Murina, et al.
Published: (2018-10-01)

Mission of polio eradication in Pakistan- a review on challenges and future recommendations
by: Abdul Rehman Shah Syed, et al.
Published: (2025-04-01)

Poliomyelitis outbreak investigation in Kayanza Health District, Burundi, 2023
by: Munekayi Padingani, et al.
Published: (2025-03-01)

The Epidemic Situation of Polio in the World in 2014 –2023
by: O. P. Chernyavskaya, et al.
Published: (2025-05-01)

Global situation for poliomyelitis. Who strategy and tactics of global polio eradication
by: M. A. Bichurina, et al.
Published: (2014-09-01)

Analysis of polio vaccination status in a cohort of live births in 2017 and 2018 in Brazilian cities: a national vaccination coverage survey
by: Alessandra Lucchesi de Menezes Xavier Franco, et al.
Published: (2024-12-01)