Sporadic detection of vaccine-derived poliovirus type 2 using next-generation sequencing in Canadian wastewater in August of 2022

Sporadic detection of vaccine-derived poliovirus type 2 using next-generation sequencing in Canadian wastewater in August of 2022

Abstract In July 2022, an unvaccinated young adult living in Rockland County, New York became paralyzed due to a vaccine-derived poliovirus type 2 (VDPV2) infection that was internationally transmitted. Wastewater surveillance in New York State uncovered VDPV2 in neighboring counties, showing silent...

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Bibliographic Details
Main Authors: Grace E. Seo, Russell Mandes, Nathan D. Wright, Justin P. Hawkins, Anneliese Landgraff, Ravinder Lidder, Umar Mohammed, Chand S. Mangat, Anne-Sophie Michel, Judith Fafard, Darian Hole, Andrea D. Tyler, Marli Vlok, Elsie Grudeski, Tim F. Booth, Anna Majer
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Poliovirus
Vaccine-derived poliovirus type 2 (VDPV2)
Wastewater surveillance
Next generation sequencing
Nanopore
Direct detection
Online Access:https://doi.org/10.1038/s41598-025-92912-x
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https://doi.org/10.1038/s41598-025-92912-x

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