Anti-<i>Trypanosoma cruzi</i> Potential of New Pyrazole-Imidazoline Derivatives

Anti-<i>Trypanosoma cruzi</i> Potential of New Pyrazole-Imidazoline Derivatives

Chagas disease, caused by <i>Trypanosoma cruzi</i>, poses a significant public health challenge due to its widespread prevalence, limited therapeutic options, and adverse effects associated with available medications. In this study, we developed 13 novel pyrazole-imidazoline derivatives,...

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Main Authors: Edinaldo Castro de Oliveira, Leonardo da Silva Lara, Lorraine Martins Rocha Orlando, Sarah da Costa Lanera, Thamyris Perez de Souza, Nathalia da Silva Figueiredo, Vitoria Barbosa Paes, Ana Carolina Mazzochi, Pedro Henrique Myra Fernandes, Maurício Silva dos Santos, Mirian Claudia de Souza Pereira
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
<i>Trypanosoma cruzi</i>
pyrazole-imidazoline
3D culture model
chemotherapy
Chagas disease
Online Access:https://www.mdpi.com/1420-3049/30/15/3082
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